Social, economic, and health indexes affecting epidemiology of preterm birth: A cross-sectional study

Shayan Mostafaei1, Alireza A Shamshirsaz2, Amir H Norooznezhad3

  • 1Department of Medical Epidemiology and Biostatistics Karolinska Institute Stockholm Sweden.

Health Science Reports
|December 11, 2023
PubMed

Insights

Economic, developmental, and health factors significantly influence preterm birth (PTB) rates globally. Understanding these factors, like prenatal care access, is crucial for accurate PTB epidemiology studies.

Area of Science:

  • Global Health
  • Epidemiology
  • Public Health Policy

Background:

  • Preterm birth (PTB) is a major cause of newborn morbidity and mortality worldwide.
  • Socioeconomic, developmental, and health factors are hypothesized to influence PTB prevalence.
  • Accurate PTB epidemiology requires understanding these potential confounding factors.

Purpose of the Study:

  • To investigate the influence of economic, human developmental, and health indexes on PTB prevalence.
  • To identify key factors associated with high and low PTB rates across countries.

Main Methods:

  • Extracted data for top 10 highest and lowest PTB prevalence countries from the Global Burden of Disease report.
  • Collected economic (income, GDP per capita), health (maternal mortality, prenatal care), and developmental (HDI) indexes from World Bank and UN.
  • Analyzed data using truncated Bayesian linear regression, decision trees, and k-means clustering.

Main Results:

  • Pregnancy Prenatal Care Rate significantly impacts PTB rates in high-prevalence countries.
  • Maternal mortality rate, human developmental index rank, and prenatal care rate affect PTB in low-prevalence countries.
  • Clustering based on socioeconomic, developmental, and health indexes closely mirrored PTB rate-based clustering (Rand index = 0.823).

Conclusions:

  • Epidemiological studies of PTB must account for socioeconomic, developmental, and health confounders.
  • These factors are critical for accurate global and nation-based PTB prevalence assessments.
  • Identifying these influences can inform targeted public health interventions.
Abstract

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