[Methanol poisoning. Clinical, neuropathologic and computerized tomography findings]

In two case reports, the characteristic clinical, CT-scan and neuropathological findings in acute methanol intoxication are described. The significance of acidosis for the survival rate and development of late sequelae is stressed. After a latency period of several days, one patient developed the rare condition of haemorrhagic leucoencephalopathy with striking CT-scan and morphological findings. The etiology of this complication is discussed. The principle therapeutic procedures including the correction of acidosis, haemodialysis and administration of ethanol and folic acid are outlined.