Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

MOSFET Amplifiers01:17

MOSFET Amplifiers

163
The MOSFET, when operating in its active region, functions as a voltage-controlled current source. In this region, the gate-to-source voltage controls the drain current. This principle underlies the operation of the transconductance MOSFET amplifier. The output current is directed through a load resistor to convert this amplifier into a voltage amplifier. The output voltage is then obtained by subtracting the voltage drop across the load resistance from the supply voltage. This process results...
163
Instrumentation Amplifier01:25

Instrumentation Amplifier

525
An electrocardiography (ECG) machine is an essential piece of medical equipment used to monitor the electrical activity of the heart. It operates by detecting small electrical changes on the skin that result from the depolarization of the heart muscle during each heartbeat. However, these signals are in the microvolt range and can be easily overwhelmed by noise or interference.
To overcome this challenge, an ECG machine utilizes an instrumentation amplifier. This specialized amplifier is...
525
Small-Signal Analysis of MOSFET Amplifiers01:23

Small-Signal Analysis of MOSFET Amplifiers

561
In small-signal analysis, a MOSFET transistor amplifier acts as a linear amplifier when operating in its saturation region. The gate-to-source voltage (VGS) of the MOSFET is the sum of the DC biasing voltage and the small time-varying input signal. This combination sets up the operating point and modulates the drain current (ID) that flows from the drain to the source. When a small AC signal is superimposed on the DC bias voltage at the gate, the instantaneous drain current comprises three...
561
Characteristics of Practical Op Amps01:16

Characteristics of Practical Op Amps

534
A difference amplifier, a crucial component in numerous electronic devices, ideally amplifies only the difference-mode signal, which is the difference between two input signals. However, in practical circuits, the output voltage depends on both the differential gain and the common-mode gain.
The ratio of differential gain to the common-mode gain is defined as the common-mode rejection ratio (CMRR). This ratio quantifies the ability of operational amplifiers (op-amps) to reject common-mode...
534
Inverting and Non-inverting OpAmps01:20

Inverting and Non-inverting OpAmps

770
In an inverting amplifier, the input voltage is connected through a resistor to the inverting terminal. Meanwhile, the non-inverting terminal is grounded and a feedback resistor is established between the inverting and output terminal, as depicted in Figure 1.
770
Operational Amplifiers01:17

Operational Amplifiers

1.0K
The operational amplifier, often referred to as an op-amp, is a multifaceted building block of a circuit. This electronic component functions like a voltage-controlled voltage source and can also be used to create a voltage- or current-controlled current source. The design of an operational amplifier enables it to execute mathematical operations when external components like resistors and capacitors are linked to its terminals. An op-amp has the capacity to sum signals, amplify a signal,...
1.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Learned spatially varying microscopy model with adaptive point spread functions.

Optics express·2026
Same author

Readout Techniques and Offset Compensation Strategies for Biomedical Resistive MEMS Sensors: A Comprehensive Review.

IEEE reviews in biomedical engineering·2025
Same author

Fully-Flexible Multifunctional Polydimethylsiloxane (PDMS) Neural Probe With a U-Turn Polyester Microchannel.

IEEE transactions on bio-medical engineering·2025
Same author

Context Informed Incremental Learning Improves Myoelectric Control Performance in Virtual Reality Object Manipulation Tasks.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same author

The Fifth Main Dynamic Factor: Skin Temperature and Its Effects on EMG-Based Gesture Recognition.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same author

Towards Next-Generation Myoelectric Prostheses: 3D-Printed Electrode Arrays for Gesture Recognition.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same journal

Analysis of End-Tidal CO2 Variability During Plateau Waves Episodes: An Information Theoretic Approach<sup></sup>.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same journal

AI and Tomosynthesis for Breast Cancer Molecular Subtyping: A step toward precision medicine<sup></sup>.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same journal

Towards Sustainable Protein Recovery from Biological Waste: Assessing Polyethersulfone-based Microfiltration.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same journal

Analysis of the cardiovascular response to standardized polymicrobial peritonitis experimental model.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same journal

Automated Wrist Ultrasound Image Bone Enhancement and Segmentation Using Deep Learning.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same journal

A Deep Learning approach for Depressive Symptoms assessment in Parkinson's disease patients using facial videos.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
See all related articles

Related Experiment Video

Updated: Jul 8, 2025

Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor
11:17

Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor

Published on: February 10, 2014

11.8K

A Low-Power High Input Range PPG Readout Amplifier with a Current Buffer Input.

Mahziar Serri Mazandarani, Gabriel Gagnon-Turcotte, Reza Papi

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |December 12, 2023
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces ultra-low power photoplethysmography (PPG) circuits for vital sign monitoring. The novel design significantly reduces power consumption, enabling continuous health tracking for respiratory diseases and drug efficacy studies.

    More Related Videos

    Recording Gap Junction Current from Xenopus Oocytes
    09:04

    Recording Gap Junction Current from Xenopus Oocytes

    Published on: January 21, 2022

    2.3K
    Fabrication of Flexible Image Sensor Based on Lateral NIPIN Phototransistors
    09:59

    Fabrication of Flexible Image Sensor Based on Lateral NIPIN Phototransistors

    Published on: June 23, 2018

    7.8K

    Related Experiment Videos

    Last Updated: Jul 8, 2025

    Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor
    11:17

    Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor

    Published on: February 10, 2014

    11.8K
    Recording Gap Junction Current from Xenopus Oocytes
    09:04

    Recording Gap Junction Current from Xenopus Oocytes

    Published on: January 21, 2022

    2.3K
    Fabrication of Flexible Image Sensor Based on Lateral NIPIN Phototransistors
    09:59

    Fabrication of Flexible Image Sensor Based on Lateral NIPIN Phototransistors

    Published on: June 23, 2018

    7.8K

    Area of Science:

    • Biomedical Engineering
    • Electrical Engineering
    • Integrated Circuit Design

    Background:

    • Vital sign monitoring is crucial for managing respiratory diseases and assessing drug safety.
    • Existing photoplethysmography (PPG) circuits often suffer from high power consumption.
    • There is a need for efficient readout circuits for continuous and remote health monitoring.

    Purpose of the Study:

    • To develop ultra-low power photoplethysmography (PPG) readout circuits.
    • To improve the power efficiency of PPG systems for vital sign monitoring.
    • To enable effective monitoring of blood pressure, heart rate, and respiratory rate.

    Main Methods:

    • Implemented a system architecture with a current buffer between the photodiode (PD) and transimpedance amplifier (TIA).
    • Utilized a Class AB amplifier topology for enhanced drive capability.
    • Employed pulse wave modulation (PWM) in the LED driver circuit to control ON/OFF times.
    • Manufactured the circuits using a 130 nm TSMC CMOS process.

    Main Results:

    • Achieved ultra-low power consumption of 3.28 µW at a 1% duty cycle and 1.2V supply voltage.
    • The current buffer effectively isolates the PD's parasitic capacitance, improving TIA power efficiency.
    • The Class AB amplifier and optimized LED driver contribute to reduced overall power usage.
    • The TIA demonstrated a maximum input current range of 160 µA, preventing saturation from large DC currents.

    Conclusions:

    • The developed ultra-low power PPG readout circuits offer a significant advancement in wearable health monitoring technology.
    • These circuits are suitable for continuous monitoring of vital signs, aiding in the study of respiratory diseases and drug efficacy.
    • The design provides a foundation for next-generation, power-efficient biomedical sensing devices.