Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Novel in silico multivariate mapping of intrinsic and anticorrelated connectivity to neurocognitive functional maps supports the maturational hypothesis of ADHD.

Human brain mapping·2018
Same author

Model order effects on ICA of resting-state complex-valued fMRI data: Application to schizophrenia.

Journal of neuroscience methods·2018
Same author

Genetics Modulate Gray Matter Variation Beyond Disease Burden in Prodromal Huntington's Disease.

Frontiers in neurology·2018
Same author

Moving Beyond ERP Components: A Selective Review of Approaches to Integrate EEG and Behavior.

Frontiers in human neuroscience·2018
Same author

A method to assess randomness of functional connectivity matrices.

Journal of neuroscience methods·2018
Same author

An ensemble learning system for a 4-way classification of Alzheimer's disease and mild cognitive impairment.

Journal of neuroscience methods·2018

Related Experiment Video

Updated: Jul 8, 2025

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
09:01

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

Published on: May 7, 2014

10.2K

How Does Aging Affect Whole-brain Functional Network Connectivity? Evidence from An ICA Method.

Yuhui Du, Yating Guo, Vince D Calhoun

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |December 12, 2023
    PubMed
    Summary

    Aging alters brain functional network connectivity (FNC) differently across networks. This study reveals specific patterns of enhanced and reduced FNC in adults aged 49-73, highlighting diverse, non-pathological brain aging trajectories.

    More Related Videos

    Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer's Disease and Mild Cognitive Impairment
    08:43

    Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer's Disease and Mild Cognitive Impairment

    Published on: August 7, 2017

    7.9K
    A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
    08:23

    A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy

    Published on: November 13, 2016

    11.2K

    Related Experiment Videos

    Last Updated: Jul 8, 2025

    A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
    09:01

    A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

    Published on: May 7, 2014

    10.2K
    Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer's Disease and Mild Cognitive Impairment
    08:43

    Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer's Disease and Mild Cognitive Impairment

    Published on: August 7, 2017

    7.9K
    A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
    08:23

    A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy

    Published on: November 13, 2016

    11.2K

    Area of Science:

    • Neuroscience
    • Aging Research
    • Brain Imaging

    Background:

    • Functional connectivity (FC) changes with age, but large-scale network alterations remain underexplored.
    • Examining gradual aging from middle to old age presents significant challenges.

    Purpose of the Study:

    • To investigate aging-related changes in functional network connectivity (FNC) across large-scale brain networks.
    • To characterize aging trajectories in functional network connectivity from middle adulthood to old age.

    Main Methods:

    • Utilized large-sample fMRI data (N=6300, ages 49-73).
    • Applied independent component analysis (ICA) via NeuroMark to identify brain networks and FNC.
    • Employed a two-level statistical analysis to detect robust aging effects on FNC.

    Main Results:

    • Enhanced FNC predominantly observed between different functional domains (e.g., default mode and cognitive control networks).
    • Reduced FNC occurred both within and between domains, notably involving visual, cognitive control networks, and the cerebellum.
    • Identified diverse patterns of FNC changes across the aging spectrum.

    Conclusions:

    • Aging impacts functional network connectivity in a diverse and network-specific manner.
    • Findings support the concept of non-pathological, varied brain aging.
    • Provides novel insights into whole-brain functional network dynamics during aging.