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    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
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    Hybrid prosthetic knees offer improved mobility for transfemoral amputees. Machine learning models, enhanced by generative adversarial networks (GANs), improve gait mode prediction for seamless transitions, boosting classifier performance.

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    Area of Science:

    • Biomedical Engineering
    • Rehabilitation Robotics
    • Machine Learning in Prosthetics

    Background:

    • Hybrid prosthetic knees integrate passive and active mechanisms for transfemoral amputees.
    • Seamless transitions between passive and active modes require accurate gait mode prediction.
    • Data imbalance poses a challenge for classifier performance in gait mode prediction.

    Purpose of the Study:

    • To evaluate machine learning classifiers for predicting passive and active gait modes in hybrid prosthetic knees.
    • To investigate the use of generative adversarial networks (GANs) for augmenting data and improving classification performance.
    • To identify optimal classifiers for real-time gait mode prediction in transfemoral amputees.

    Main Methods:

    • Collected gait data from nine unilateral transfemoral amputees during various ambulation tasks (level ground, inclines, stairs).
    • Evaluated multiple machine learning classifiers (e.g., linear discriminant analysis, random forest) for gait mode prediction.
    • Developed and applied a generative adversarial network (GAN) to generate synthetic data for classifier training.

    Main Results:

    • Linear discriminant analysis showed high sensitivity for the active mode (stair ascent).
    • Random forest achieved the highest overall classification accuracy.
    • Training classifiers with GAN-generated synthetic data significantly improved classifier sensitivity.

    Conclusions:

    • Machine learning, particularly linear discriminant analysis and random forest, shows promise for gait mode prediction in hybrid prosthetic knees.
    • Generative adversarial networks effectively address data imbalance, enhancing classifier performance.
    • Improved gait mode prediction can lead to more intuitive and responsive prosthetic knee control for transfemoral amputees.