Related Experiment Video
Updated: Jul 8, 2025

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
Dercum's Disease: A Rare Disease of Painful Fatty Lumps
Alsadat Mosbeh1,2, Rawan Almutairi3, Abeer Albazzali3
1Department of Dermatopathology, Farwaniya Hospital, Ministry of Health, Sabah Al Nasser, KWT.
Abstract:
Dercum's disease is a rare and poorly understood condition characterized by painful subcutaneous adipose tissue growth that can occur anywhere beneath the skin surface. We present the case of a 27-year-old man with no significant medical history who had been experiencing painful subcutaneous nodules for two years. Skin biopsy revealed the proliferation of mature adipocytes that were surrounded by fibrous septa. There are currently no treatments approved by the US Food and Drug Administration for Dercum's disease, and the effectiveness of treatments that have been attempted is variable.
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