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Published on: November 30, 2022
Patients with COVID-19 Pneumonia Admitted to an Intensive Care Unit (ICU) at a Community Hospital in Flint, Michigan,
Atefeh Kalantary1, Olga J Santiago-Rivera2, Arunima Dutta3
1Medical Director Menalam Health Services PC, Simi Valley, CA.
Introduction:
Despite the many studies conducted on the factors affecting mortality in patients with COVID-19, there is ongoing debate about the role of race as a risk factor. Several studies have reported a geographic and racial disparity in COVID-19 cases in Michigan. This study aimed to examine the characteristics of the 2020 first cohort of Intensive Care Unit (ICU) COVID-19 patients admitted to a community teaching hospital in Flint, Michigan, and to determine the factors associated with ICU mortality, including race.
Methods:
This cross-sectional study included adult patients (≥ 18 years) with severe COVID-19 pneumonia admitted to the ICU between March and May 2020. Potential risk factors associated with ICU mortality included demographic characteristics, comorbidities, treatments, and complications.
Results:
The study sample consisted of N = 48 patients, aged 24-85 years, (mean 59.7; SD = 12.8); 56.2% (n=27) were male and 51.1% (n=24) were Black adults. The mortality rate was 51.1%. Age (aOR 1.1, 95% CI [1.01, 1.20]; p =0.03), type 2 diabetes (aOR 5.7, 95% CI [1.2, 29.1]; p =0.03), and essential hypertension (aOR 6.2, 95% CI [1.1, 34.5]; p =0.04) were all found to have statistically significant independent associations with increased risk of ICU mortality in this study sample. On the other hand, race was not found to be associated with ICU mortality.
Conclusions:
These findings support the literature regarding the association of comorbid conditions, including type 2 diabetes and hypertension, with poorer outcomes in ICU hospitalized patients with severe COVID-19 pneumonia. This study provides insight into mortality of an ICU patient cohort earlier on during the COVID-19 pandemic in Flint, Michigan.
Insights
In critically ill COVID-19 patients, type 2 diabetes and hypertension, not race, independently increased the risk of intensive care unit (ICU) mortality. These comorbidities are crucial factors in COVID-19 outcomes.
Area of Science:
- Critical Care Medicine
- Infectious Diseases
- Epidemiology
Background:
- COVID-19 pandemic highlighted racial disparities in outcomes.
- Ongoing debate exists regarding race as an independent risk factor for COVID-19 mortality.
- Michigan reported significant geographic and racial disparities in COVID-19 cases.
Purpose of the Study:
- To examine characteristics of early COVID-19 intensive care unit (ICU) patients in Flint, Michigan.
- To identify factors associated with ICU mortality in this cohort.
- To specifically investigate the role of race in ICU mortality.
Main Methods:
- Cross-sectional study of adult patients with severe COVID-19 pneumonia admitted to ICU.
- Data collected between March and May 2020.
- Analyzed demographic characteristics, comorbidities, treatments, and complications as potential risk factors.
Main Results:
- The study included 48 patients (51.1% Black adults, 56.2% male), with a 51.1% ICU mortality rate.
- Age, type 2 diabetes, and essential hypertension were independently associated with increased ICU mortality.
- Race was not found to be significantly associated with ICU mortality in this cohort.
Conclusions:
- Comorbid conditions like type 2 diabetes and hypertension are linked to poorer outcomes in severe COVID-19 pneumonia.
- This study offers insights into the mortality of an early ICU COVID-19 patient cohort in Flint, Michigan.
- Findings underscore the importance of managing comorbidities in critically ill COVID-19 patients.
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