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Related Experiment Videos

Ketonuria in normal pregnancy.

R A Chez, F D Curcio

    Obstetrics and Gynecology
    |February 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Ketonuria, or ketone bodies in urine, is common in normal pregnancies. This study found sporadic acetoacetonuria in most pregnant women, unrelated to gestation length or time of day.

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    Area of Science:

    • Obstetrics and Gynecology
    • Clinical Chemistry
    • Metabolic Disorders

    Background:

    • Pregnancy involves significant metabolic changes.
    • Ketonuria can indicate altered metabolic states.
    • Understanding ketonuria in normal pregnancy is important for accurate diagnosis.

    Purpose of the Study:

    • To investigate the occurrence and pattern of ketonuria in clinically normal, low-risk pregnant women.
    • To determine if ketonuria is related to gestational stage or time of day.

    Main Methods:

    • Urine samples were collected from nine low-risk pregnant women at 3-4 day intervals throughout gestation.
    • Samples were tested for the presence of ketone bodies (acetoacetonuria).

    Main Results:

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    • Eight out of nine women exhibited acetoacetonuria on 2 to 15 separate occasions.
    • The presence of ketonuria was not correlated with the length of gestation.
    • Ketonuria occurrence was independent of the time of day the urine sample was collected.

    Conclusions:

    • Sporadic ketonuria is a common finding in uncomplicated pregnancies.
    • This suggests a degree of metabolic variability is normal during gestation.
    • Routine screening for ketonuria in asymptomatic pregnant women may not be necessary.