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Natural course of AIDS following HIV-2 infection

Hannah Fuhr1, Maximilian Christopeit2,3

  • 1Outpatient Practice for Primary Care and Infectious Disease (Gemeinschaftspraxis, Drs Frietsch, Roll, Marquardt), Stuttgart, Germany.

Infection
|December 12, 2023
PubMed

In a 21-year-old female, AIDS following infection with HIV-2 was diagnosed alongside an HIV-associated high-grade B cell lymphoma. Treatment of HIV-2 with dolutegravir, emtricitabine, and tenofovir resulted in viral suppression and slow recovery of CD4 cell counts. Treatment of lymphoma caused significant adverse effects but led to complete remission. The patient denied sexual activity and intravenous drug abuse. The patient had been born to an HIV-2-positive mother but appropriate perinatal testing based on national guidelines had remained negative. This case recapitulates the natural course of HIV-2 infection.

Keywords:
AIDSHIV2Lymphoma

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