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Updated: Jul 8, 2025
A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
Hepatocellular carcinoma
Cristina Dopazo1, Kjetil Søreide2, Elena Rangelova3
1Department of HPB Surgery and Transplants, Vall d'Hebron Hospital Universitari, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, Universitat Autónoma de Barcelona, Barcelona, Spain.
This article updates Hepatocellular carcinoma (HCC) management, covering surveillance, guidelines, and treatments like resection, transplantation, and therapies. It focuses on core curriculum points for hepatobiliary oncological surgery exams.
Area of Science:
- Hepatobiliary Oncological Surgery
- Surgical Oncology
Background:
- Hepatocellular carcinoma (HCC) is a significant global health concern.
- Effective management requires up-to-date knowledge of evolving treatment strategies.
Purpose of the Study:
- To provide a comprehensive update on Hepatocellular carcinoma (HCC) management.
- To outline key information for the UEMS/EBSQ exam in Surgical Oncology.
- To summarize essential points for the hepatobiliary oncological surgery core curriculum.
Main Methods:
- Review of recent publications on HCC.
- Synthesis of current guidelines and treatment indications.
- Focus on surveillance, liver resection, liver transplantation, locoregional, and systemic therapies.
Main Results:
- Summarized recent advancements in HCC surveillance and treatment.
- Detailed indications for surgical and non-surgical interventions.
- Consolidated core curriculum content for surgical oncology.
Conclusions:
- The article provides a focused update on Hepatocellular carcinoma (HCC) management.
- It serves as a valuable resource for surgical oncology trainees and practitioners.
- Key information for hepatobiliary oncological surgery is highlighted.
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