Related Experiment Video
Updated: Jul 8, 2025
07:27
Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
Published on: August 25, 2021
1.9K
The Risk of Sympathetic Ophthalmia Associated with Open-Globe Injury Management Strategies: A Meta-analysis
Tim J Patterson1, Adam Kedzierski2, David McKinney1
1Northern Ireland Medical and Dental Training Agency (NIMDTA), Beflast, United Kingdom.
Ophthalmology
|December 12, 2023
Summary
This review found no evidence that removing or eviscerating an injured eye reduces sympathetic ophthalmia (SO) risk compared to primary repair. Current data suggests similar outcomes for both strategies in managing open-globe injuries.
Area of Science:
- Ophthalmology
- Immunology
- Trauma Surgery
Background:
- Sympathetic ophthalmia (SO) is a severe bilateral granulomatous panuveitis following ocular trauma or surgery.
- The optimal management strategy for open-globe injury (OGI) to prevent SO remains a subject of debate.
- Primary enucleation or evisceration versus primary repair strategies are compared for risk management.
Conclusions:
- Current evidence does not support the hypothesis that primary enucleation or evisceration reduces the risk of sympathetic ophthalmia.
- The observed differences in SO rates between surgical strategies are not statistically significant.
- Further high-quality research is needed to definitively establish the optimal management for OGI regarding SO prevention.
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