Related Experiment Video
Updated: Jul 8, 2025

An “All-laser” Endothelial Transplant
Published on: July 6, 2015
Femtosecond laser-assisted corneal transplantation
Chang Liu1,2, Jodhbir S Mehta1,2,3,4, Yu-Chi Liu1,2,3,4,5
1Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore.
Femtosecond laser (FSL) enhances corneal transplantation precision for better vision. While FSL offers customization in keratoplasty, cost-effectiveness remains a barrier to widespread adoption.
Area of Science:
- Ophthalmology
- Biomedical Engineering
Background:
- Corneal opacification severely impacts vision, with transplantation being the primary treatment.
- Advancements in keratoplasty techniques allow for customized procedures and improved patient outcomes.
Purpose of the Study:
- To review the intraoperative applications and postoperative outcomes of femtosecond laser (FSL)-assisted keratoplasties.
- To evaluate the role of FSL in various corneal transplantation techniques.
Main Methods:
- Review of literature on FSL applications in corneal transplantation.
- Summary of outcomes for penetrating keratoplasty, anterior lamellar keratoplasty (ALK), deep ALK, Descemet stripping automated endothelial keratoplasty (EK), and Descemet membrane EK.
Main Results:
- FSL enables precise customization of graft thickness and shape, and facilitates complex graft-host junctions.
- FSL has been applied across multiple keratoplasty types, including ALK and EK variations.
Conclusions:
- FSL-assisted keratoplasty offers enhanced precision and customization in corneal transplantation.
- Further research is needed to address cost-effectiveness and fully assess the advantages versus limitations of FSL in clinical practice.
More Related Videos
12:36A Human Corneal Organ Culture Model of Descemet's Stripping Only with Accelerated Healing Stimulated by Engineered Fibroblast Growth Factor 1
Published on: July 22, 2022
05:46Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity
Published on: September 20, 2024