[Update on functional mitral regurgitation: a comprehensive review]

Area of Science:

• Cardiology
• Cardiac Physiology

Context:

• Functional mitral regurgitation (MR) prevalence increases in patients over 50.
• Advances in MR management necessitate updated clinical knowledge.

Purpose:

• Review the pathophysiological basis of functional MR.
• Differentiate MR mechanisms.
• Correlate clinical, hemodynamic, and imaging findings with MR severity.

Summary:

• This review details the pathophysiology of functional MR, distinguishing its mechanisms.
• It links clinical presentation, hemodynamic data, and imaging results to disease severity.
• This information aids in patient selection and timing of therapeutic interventions.

Impact:

• Facilitates appropriate patient selection for MR interventions.
• Guides optimal timing for therapeutic interventions.
• Supports multidisciplinary team decision-making for improved patient outcomes.