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The Burden of Human Parechoviruses Among Children in Oman: A retrospective study

Aws Al-Farsi1, Zaid Alhinai1, Fatma Ba Alawi2

  • 1College of Medicine and Health Sciences, Sultan Qaboos University, Sultan Qaboos University Hospital, Muscat, Oman.

Sultan Qaboos University Medical Journal
|December 13, 2023
PubMed

Insights

Human parechoviruses (HPeVs) infections in Omani children are common, often occurring with other viruses and typically resulting in full recovery. Further follow-up for neurological outcomes is needed.

Area of Science:

  • Pediatric Infectious Diseases
  • Virology
  • Public Health

Background:

  • Human parechoviruses (HPeVs) are a group of viruses that can cause illness in children.
  • Understanding the epidemiology and clinical presentation of HPeV infections is crucial for effective management.

Purpose of the Study:

  • To evaluate the burden, clinical and laboratory features, and outcomes of HPeV infections in children in Oman.
  • To describe the demographic characteristics and common comorbidities of affected children.

Main Methods:

  • A retrospective study was conducted analyzing data from children (<18 years) with molecularly confirmed HPeV infection.
  • Data were collected from medical records at Sultan Qaboos University Hospital, Muscat, Oman (January 2017-December 2019).
  • Demographics, clinical presentation, laboratory findings, management, and outcomes were analyzed.

Main Results:

  • HPeV was detected in 61 children, predominantly males (72%), with a median age of nine months.
  • Most infections occurred year-round, with 84% of patients having co-infections and 79% requiring hospitalization.
  • Fever and cough were common symptoms; lower respiratory tract infections were frequent, while meningitis and gastroenteritis were rare. All patients recovered fully.

Conclusions:

  • HPeV infections in Omani children lack clear seasonality, often present with viral co-infections, and generally have favorable outcomes.
  • While no mortalities were observed, a lack of thorough neurological outcome follow-up was noted.
Abstract

Keywords:
ChildrenInfectionOmanParechovirusPatient Outcome Assessment

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