Lithium induced chronic renal disease: A case report

Area of Science:

• Nephrology
• Psychiatry
• Pharmacology

Background:

• Lithium is a common mood stabilizer for bipolar disorder.
• Long-term lithium treatment is associated with various renal complications.
• Chronic kidney disease (CKD) is a potential adverse effect of lithium therapy.

Observation:

• A 69-year-old female with hypertension and bipolar disorder was treated with lithium.
• The patient developed chronic renal disease during long-term lithium treatment.

Findings:

• The case demonstrates a direct correlation between sustained lithium administration and the development of lithium-induced CKD.
• Renal biopsy findings (if available) would further confirm the diagnosis.

Implications:

• This case underscores the necessity of regular renal function monitoring in patients on long-term lithium.
• Clinicians should consider alternative treatments or dose adjustments to mitigate nephrotoxicity risks.
• Early detection and intervention are crucial for managing lithium-induced nephropathy.