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Updated: Jul 8, 2025

Closure of a Patent Foramen Ovale PFO: An Intervention Sequence
Published on: December 23, 2022
VA-ECMO-Facilitated Clot Debulking and PFO Closure in a Patient With Recurrent Pulmonary Thromboses
Kathryn Harris1, Javier Farinas1, Jamie Lesnock1
1University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Abstract:
A 27-year-old female with stage IIIc cervical cancer presented with dyspnea and stroke symptoms. Work-up revealed bilateral pulmonary embolisms, acute/subacute strokes, and a patent foramen ovale. After multidisciplinary team discussion, the patient underwent patent foramen ovale closure, complicated by cardiogenic shock requiring venoarterial extracorporeal membrane oxygenation. She successfully underwent pulmonary thromboendarterectomy, extracorporeal membrane oxygenation decannulation, and hospital discharge.
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