Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Potential Due to a Polarized Object01:29

Potential Due to a Polarized Object

415
A neutral atom consists of a positively charged nucleus surrounded by a negatively charged electron cloud. When placed in an external electric field, the external electric force pulls the electrons and nucleus apart, opposite to the intrinsic attraction between the nucleus and the electrons. The opposing forces balance each other with a slight shift between the center of masses of the nucleus and the electron cloud, resulting in a polarized atom. On the other hand, a few molecules, like water,...
415
The Resting Membrane Potential01:21

The Resting Membrane Potential

132.5K
Overview
132.5K
Charge on a Conductor01:26

Charge on a Conductor

4.5K
An interesting property of a conductor in static equilibrium is that extra charges on the conductor end up on its outer surface, regardless of where they originate. Consider a hollow metallic conductor with a uniform surface charge density. Since the conductor itself is in electrostatic equilibrium, there should not be any electric field inside the conductor. Now, assume a Gaussian surface enclosing the hollow portion. Applying Gauss's law, the inner surface of the hollow conductor will not...
4.5K
Electrostatic Boundary Conditions01:16

Electrostatic Boundary Conditions

480
Consider an external electric field propagating through a homogeneous medium. When the electric field crosses the surface boundary of the medium, it undergoes a discontinuity. The electric field can be resolved into normal and tangential components. The amount by which the field changes at any boundary is given by the difference between the field components above and below the surface boundary.
The surface integral of an electric field is given by Gauss's law in integral form and is related to...
480
Resting Membrane Potential01:24

Resting Membrane Potential

18.6K
The relative difference in electrical charge, or voltage, between the inside and the outside of a cell membrane, is called the membrane potential. It is generated by differences in permeability of the membrane to various ions and the concentrations of these ions across the membrane.
The Inside of a Neuron is More Negative
The membrane potential of a cell can be measured by inserting a microelectrode into a cell and comparing the charge to a reference electrode in the extracellular fluid. The...
18.6K
Electric Field of a Non Uniformly Charged Sphere01:22

Electric Field of a Non Uniformly Charged Sphere

1.5K
Gauss's law states that the electric flux through any closed surface equals the net charge enclosed within the surface. This law is beneficial for determining the expressions for the electric field for a particular charge distribution if the electric flux is known.
Consider a non-uniformly charged sphere, for which the density of charge depends only on the distance from a point in space and not on the direction. Such a sphere has a spherically symmetrical charge distribution. Here, the electric...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A proliferation-inducing ligand enhances the anti-tumor effect of BCMA CAR T-cell through inhibition of soluble BCMA.

Biochimica et biophysica acta. Molecular basis of disease·2026
Same author

DiRT v2.0: An Optimized Pipeline for Detecting Dicistronic tRNA-mRNA Transcripts in Plants.

Bio-protocol·2026
Same author

Safety and efficacy of distal versus conventional radial artery cannulation for invasive blood pressure monitoring: a systematic review and meta-analysis.

Journal of clinical monitoring and computing·2026
Same author

Research of Tuberous Sclerosis Complex (TSC)-Associated Neuropsychiatric Disorders (TAND) in China.

Pediatric neurology·2026
Same author

A Delphi Study on the Development of a Traditional Chinese Medicine Syndrome-Differentiation Nursing Framework for Patients with Cirrhotic Ascites.

Journal of multidisciplinary healthcare·2026
Same author

A polymicrobial opportunistic infection leading to osteolytic destruction and acute respiratory failure: a case report.

BMC infectious diseases·2026
Same journal

Revisiting, Understanding, and Tailoring the Evolution in the Nature of Phase Transitions in Rare-Earth RE<sub>2</sub>In Alloys.

The journal of physical chemistry letters·2026
Same journal

Room-Temperature Quasi-CW Random Lasing in a Tin-Perovskite Ultrathin Film.

The journal of physical chemistry letters·2026
Same journal

Emerging Electride Behavior and Metallization in Molecular Hydrogen under High Pressure.

The journal of physical chemistry letters·2026
Same journal

Surface Electrochemistry of Au(111) in Acetonitrile Based Electrolytes: Formation of a Solvent Related Adsorbed Layer.

The journal of physical chemistry letters·2026
Same journal

Asymmetric Hydration Shell Reveals Interfacial TFSI Organization in Imidazolium Ionic Liquid Films.

The journal of physical chemistry letters·2026
Same journal

Turning 3D Molecular Crystals into 2D Moiré Superlattices with Properties Born Out of Bonding at the Angularly Stacked Interfaces.

The journal of physical chemistry letters·2026
See all related articles

Related Experiment Video

Updated: Jul 8, 2025

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores
09:43

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores

Published on: October 31, 2013

13.5K

Ion Concentration-Dependent Surface Charge Density Inside a Nanopore.

Lijian Zhan1, Zhenyu Zhang1, Fei Zheng1

  • 1Jiangsu Key Laboratory for Design and Manufacture of Micro-Nano Biomedical Instruments, School of Mechanical Engineering, Southeast University, Nanjing 211189, China.

The Journal of Physical Chemistry Letters
|December 14, 2023
PubMed
Summary
This summary is machine-generated.

Researchers developed a new method using solid-state nanopores to measure surface charge density in confined spaces. Surface charge density decreases with lower salt concentrations and smaller nanopore sizes, offering insights for nanofluidic device design.

More Related Videos

Monitoring Protein Adsorption with Solid-state Nanopores
08:51

Monitoring Protein Adsorption with Solid-state Nanopores

Published on: December 2, 2011

13.6K
High Resolution Physical Characterization of Single Metallic Nanoparticles
09:56

High Resolution Physical Characterization of Single Metallic Nanoparticles

Published on: June 28, 2019

5.8K

Related Experiment Videos

Last Updated: Jul 8, 2025

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores
09:43

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores

Published on: October 31, 2013

13.5K
Monitoring Protein Adsorption with Solid-state Nanopores
08:51

Monitoring Protein Adsorption with Solid-state Nanopores

Published on: December 2, 2011

13.6K
High Resolution Physical Characterization of Single Metallic Nanoparticles
09:56

High Resolution Physical Characterization of Single Metallic Nanoparticles

Published on: June 28, 2019

5.8K

Area of Science:

  • Surface chemistry
  • Nanotechnology
  • Electrokinetics

Background:

  • Surface charges at solid-liquid interfaces dictate electrical double layer (EDL) structure.
  • EDL properties are crucial for energy storage and micro/nanofluidic devices.
  • Measuring surface charge density in nanoconfined environments presents significant challenges.

Purpose of the Study:

  • To introduce a novel methodology for characterizing surface charge density in nanoconfined spaces.
  • To investigate the influence of salt concentration and nanopore diameter on surface charge density.
  • To provide a foundation for designing advanced electrokinetically driven nanofluidic systems.

Main Methods:

  • Utilized solid-state nanopores as a platform for surface charge density measurements.
  • Systematically varied salt concentrations in bulk solutions and nanopore diameters.
  • Integrated experimental measurements with a complementary theoretical model.

Main Results:

  • Demonstrated that surface charge density decreases with reduced salt concentrations.
  • Observed a decrease in surface charge density with smaller nanopore sizes.
  • Identified a critical salt concentration (below 10-3 M) where proton conductance dominates, leading to constant surface charge density.

Conclusions:

  • The developed methodology offers an effective approach for surface charge characterization in nanoconfined systems.
  • Findings highlight the tunable nature of surface charge density based on environmental conditions and confinement.
  • The study provides valuable insights for the rational design of nanofluidic devices and electrokinetic phenomena.