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Invasively measured and estimated central blood pressure using the oscillometric algorithm Antares in patients with

Alexander Stäuber1, Marcus Dörr2, Cornelia Piper3

  • 1Department of Movement and Training Science, Leipzig University, Leipzig, Germany.

Plos One
|December 14, 2023
PubMed

Insights

Obesity does not significantly alter central blood pressure (cBP), but women, particularly obese women, show higher cBP. The Antares algorithm accurately estimates non-invasive cBP in obese patients.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Obesity Medicine

Background:

  • Obesity is a global health issue and a cardiovascular disease risk factor.
  • Central blood pressure (cBP) assessment aids cardiovascular event prediction.
  • Limited invasive data exists on obesity's impact on cBP.

Purpose of the Study:

  • Evaluate cBP differences between obese and non-obese adults.
  • Identify determinants of cBP.
  • Assess the accuracy of the Antares algorithm for non-invasive cBP estimation.

Main Methods:

  • Invasive and non-invasive cBP measurements in 190 cardiac catheterization patients.
  • Included 39% obese patients (BMI ≥30kg/m2).
  • Used custo screen 400 device with Antares algorithm.

Main Results:

  • No significant cBP differences between obese and non-obese groups.
  • Obese females exhibited higher systolic cBP than males.
  • Brachial pressure, BMI, and heart rate predicted cBP (adjusted R2 = 0.82).
  • Antares showed strong correlation (r=0.74-0.93) and accuracy for non-invasive cBP.

Conclusions:

  • No significant cBP difference found between obese and non-obese patients.
  • Higher cBP in obese women warrants further investigation.
  • Antares algorithm effectively estimates non-invasive cBP in obese individuals, aiding hypertension management.
Abstract

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