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Updated: Jul 8, 2025

A Multi-detection Assay for Malaria Transmitting Mosquitoes
Published on: February 28, 2015
Vivax malaria and Duffy antigen: Stop being so negative
Patrick E Duffy1, Karthigayan Gunalan2, Louis H Miller2
1Laboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA.
Abstract:
Duffy blood group antigen (Duffy antigen/receptor for chemokines, atypical chemokine receptor-1, Duffy antigen), an essential Plasmodium vivax invasion receptor, is absent in most Africans. In this issue, two papers show erythroid precursors from Duffy-negative individuals transiently surface-express Duffy antigen and support vivax infection, potentially explaining low-density vivax infections across Africa.
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