[Changes in the motor activity of an isolated intestinal loop from the jejunum of dogs exposed to an endotoxin]

The author examined the motor activity of an isolated Loop in vivo of founonnarcotised dogs under the conditions of chronic experiments before and after administration of E. coli in dose of 0.1, 0.5, 1.0, and 2.0 mg/body weight. There was inhibition of the movements of the intestinal loop, which was manifested by a reduction of the frequency and amplitude of the intestinal contractions. The inhibition of the motor activity was explained by the disturbances in the circulation and neuro-bunoral control of the intestinal smooth muscle.