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Profiling of Estrogen-regulated MicroRNAs in Breast Cancer Cells
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Profiling of Estrogen-regulated MicroRNAs in Breast Cancer Cells

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Response to: Correspondence on 'MicroRNA expression as a diagnostic parameter in early endometrial cancer' by Coada

Stefan Blagojević1, Milena Milutinović2, Danijela Cvetković3

  • 1University of Kragujevac, Faculty of Science, Kragujevac, Serbia stefan.blagojevic@pmf.kg.ac.rs.

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
|December 14, 2023
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Area Under CurveUterine Cancer

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MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...