Recurrent Transient Hypoxemia in a Schizophrenic Patient Caused by Upper Airway Foreign Body Obstruction by

Kaori Amari1, Risa Hirata2, Masaki Tago2

  • 1Department of Emergency Medicine, Saga-Ken Medical Centre Koseikan, Saga, JPN.

Cureus
|December 15, 2023
PubMed

A woman in her 70s with schizophrenia experienced repeated episodes of limb tremors and hypoxemia. Even after admission, the same symptoms continued while in a supine position. However, her condition rapidly improved with bag valve mask ventilation. Although computed tomography suggested aspiration pneumonia, she had a strong cough reflex while performing bronchoscopy, and no residues were observed in the trachea. Following the bronchoscopy examination, the patient was prompted by a nurse and subsequently expelled a mass of watermelon from her oral cavity, which was identified as a watermelon eaten during breakfast on the day. She was diagnosed with aspiration pneumonia, and treatment with 2 g/day of cefotiam was initiated. The inflammatory response had improved, and she was transferred to another hospital for adjustment of psychiatric medications on the 10th day of admission. A study indicated that 77% of emergency medical staff experienced misdiagnosis or delayed diagnosis of patients with mental illnesses. In the present case, various biases and system factors were found to be involved in the diagnostic error. It is crucial to recognize the potential for diagnostic errors in managing patients with schizophrenia given the various biases that may come into play. Furthermore, patients with schizophrenia are at high risk of upper airway foreign body obstruction because of dysphagia or drug-induced effects. When transient hypoxemia is observed, a prompt assessment of the visible intraoral region and, if necessary, evaluation of the entire upper airway through imaging studies should be considered.

Related Concept Videos

Alterations in Respiration II01:30

Alterations in Respiration II

There are numerous types of normal and abnormal respiration. Based on ventilatory movements, breathing patterns are classified as regular, deep, or shallow. Examples include Biot's breathing, Cheyne-Stokes respiration, Kussmaul's breathing, hyperventilation, and hypoventilation. Each pattern is clinically significant and aids in evaluating patients.
In Biot's breathing, the respiratory rate and depth are irregular, alternating between periods of deep gasping and apnea. Common causes...
869
Acute Respiratory Failure-III01:30

Acute Respiratory Failure-III

Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
187
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
239
Acute Respiratory Failure-IV01:23

Acute Respiratory Failure-IV

Respiratory failure can manifest suddenly or gradually, characterized by a rapid decline in PaO2 and a rapid rise in PaCO2. This situation indicates a severe respiratory problem that may quickly become a life-threatening emergency. One of the early signs of hypoxemic Acute Respiratory Failure (ARF) is a change in mental status due to the brain's sensitivity to oxygen levels and changes in acid-base balance. Symptoms such as restlessness, confusion, and agitation suggest inadequate oxygen...
159
Hyperpnea and Hyperventilation01:25

Hyperpnea and Hyperventilation

Hyperventilation refers to a higher-than-normal rate and depth of breathing, often associated with anxiety attacks. This excessive breathing surpasses the body's need to expel CO2, leading to a condition known as hypocapnia - an unusually low level of carbon dioxide in the blood. Hypocapnia can constrict cerebral blood vessels, reducing blood flow to the brain, which may result in dizziness or fainting. Early signs include tingling and muscle spasms in the hands and face, caused by falling...
1.1K
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
242