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Updated: Jul 8, 2025

The Development of Lyophilized Loop-mediated Isothermal Amplification Reagents for the Detection of Coxiella burnetii
Published on: April 18, 2016
Molecular prevalence of Coxiella burnetii in cheese samples: Systematic review and meta-analysis
Berna Yanmaz1, Ediz Kagan Ozgen2
1Department of Public Health, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University, Burdur, Turkey.
Background:
Cheese is a popular dairy product consumed worldwide, and it has been implicated as a source of Coxiella burnetii infections.
Objectives:
The present study aimed to describe the molecular prevalence and source analysis of C. burnetii in cheese samples.
Methods:
A systematic literature search was conducted using the Medline/PubMed, Science Direct, Web of Science, Scopus, and Google Scholar databases to identify studies reporting the molecular prevalence of C. burnetii in cheese samples. The pooled prevalence of C. burnetii in cheese samples was estimated using a random-effects model.
Results:
A meta-analysis was conducted using the mean and standard deviation values obtained from 13 original studies. The overall molecular prevalence of C. burnetii in cheese was estimated to be 25.2% (95% confidence interval [CI]: 13.1%-39.7%). The I2 value of 96.3% (CI95% 94.9-97.3) suggested high heterogeneity, with a τ2 of 0.642 (CI95% -0.141 to 0.881), and an χ2 statistic of 323.77 (p < 0.0001).
Conclusions:
In conclusion, our meta-analysis provides a thorough assessment of the molecular prevalence and source analysis of C. burnetii in cheese samples.
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