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Related Experiment Videos

Polyuria among patients with psychosis.

W V Vieweg, J J David, J L Glick

    Schizophrenia Bulletin
    |January 1, 1986
    PubMed
    Summary

    Polyuria, defined by low urinary specific gravity (SPGR), was common in chronically psychotic patients. Lithium use was linked to polyuria in men, suggesting a need for monitoring.

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    Area of Science:

    • Nephrology
    • Psychiatry
    • Endocrinology

    Background:

    • Polyuria is a condition characterized by excessive urination.
    • Chronic psychosis affects a significant patient population, often requiring long-term institutionalization.
    • Understanding the prevalence and potential causes of polyuria in this demographic is crucial for patient care.

    Purpose of the Study:

    • To determine the prevalence of polyuria in institutionalized chronically psychotic patients.
    • To investigate potential factors associated with polyuria in this population, including diagnosis, sex, age, weight, serum sodium, and lithium administration.
    • To explore the utility of urinary creatinine concentration (UCR) as an alternative marker for polyuria.

    Main Methods:

    • Utilized early morning urinary specific gravity (SPGR) ≤ 1.008 as the criterion for defining polyuria.

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  • Conducted a comprehensive survey in a chronic care unit of a State mental hospital.
  • Analyzed demographic, clinical, and laboratory data, including serum sodium and UCR.
  • Main Results:

    • Identified polyuria in 36% of male and 45% of female institutionalized chronically psychotic patients.
    • Found no significant differences in polyuria prevalence based on diagnosis, sex, age, weight, or serum sodium.
    • Observed an association between lithium administration and polyuria in male patients.
    • Demonstrated a strong correlation between SPGR and UCR, suggesting UCR as a potential alternative index.

    Conclusions:

    • Polyuria is prevalent in institutionalized chronically psychotic patients.
    • Lithium treatment may be a contributing factor to polyuria in men with chronic psychosis.
    • Urinary creatinine concentration (UCR) shows promise as a reliable alternative to SPGR for identifying polyuria in this population.