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Related Experiment Videos

[Renal involvement in Legionnaires' disease].

H Heule, F W Reutter, F Gloor

    Schweizerische Medizinische Wochenschrift
    |December 6, 1986
    PubMed
    Summary

    Legionnaires' disease can cause kidney problems, including acute renal insufficiency and urinary abnormalities. These kidney issues were often reversible, even in patients requiring dialysis.

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    Glomerulopathy associated with predominant fibronectin deposits: a newly recognized hereditary disease.

    Kidney international·1995

    Area of Science:

    • Nephrology
    • Infectious Diseases

    Context:

    • Legionnaires' disease, a severe pneumonia, can have extrapulmonary manifestations.
    • Renal involvement in Legionnaires' disease is not well-characterized.

    Purpose:

    • To investigate the spectrum and reversibility of renal abnormalities in patients with Legionnaires' disease.

    Summary:

    • Nine consecutive Legionnaires' disease cases presented with pathological urinary sediment or acute renal insufficiency.
    • Six patients had acute renal insufficiency, four requiring dialysis; proteinuria, hematuria, leukocyturia, and cylindruria were also observed.
    • Renal biopsies revealed acute interstitial nephritis or diffuse sclerosing interstitial nephritis in two patients; others had pre-existing renal pathology. Renal failure and urinary abnormalities were largely reversible.

    Impact:

    • Highlights the significant renal impact of Legionnaires' disease.
    • Suggests prompt diagnosis and management may lead to renal recovery.
    • Underscores the importance of considering renal function in Legionnaires' disease patients.

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