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Updated: Jul 8, 2025

Culture and Imaging of Ex Vivo Organotypic Pseudomyxoma Peritonei Tumor Slices from Resected Human Tumor Specimens
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The Cancer Diaspora: A Rare Case of Pseudomyxoma Peritonei of Appendiceal Origin

Lefika Bathobakae1, Sacide S Ozgur1, Mohita Jariwala2

  • 1St. Joseph's University Medical Center, Paterson, NJ, USA.

Journal of Investigative Medicine High Impact Case Reports
|December 15, 2023
PubMed

Insights

Pseudomyxoma peritonei (PMP) is a rare condition causing widespread mucinous implants. This case highlights a PMP diagnosis in a 59-year-old woman, potentially benefiting from future HIPEC treatment.

Area of Science:

  • Oncology
  • Gastroenterology

Background:

  • Pseudomyxoma peritonei (PMP) is a rare malignancy characterized by mucinous ascites and peritoneal implants.
  • While commonly originating from the appendix, PMP can arise from other gastrointestinal or ovarian sources, with colorectal origin indicating a poorer prognosis.

Observation:

  • A 59-year-old Hispanic woman presented with a 3-month history of progressive abdominal distention.
  • Computed tomography (CT) scan and histopathology confirmed PMP with extensive carcinomatosis.

Findings:

  • The patient underwent partial cytoreductive surgery.
  • Despite extensive disease, her Eastern Cooperative Oncology Group (ECOG) performance status was 1.

Implications:

  • This case underscores the importance of considering PMP in patients with unexplained abdominal distention.
  • The patient's performance status suggests potential eligibility for hyperthermic intraperitoneal chemotherapy (HIPEC) as an adjuvant therapy.
Keywords:
Pseudomyxoma peritoneicomplete cytoreductive therapyhyperthermic intraperitoneal chemotherapyjelly bellymucinous ascites

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