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Published on: December 1, 2017
The roles of pyroptosis in genitourinary diseases
Haopeng Liu1, Haoran Liu1, Guoshuai Huang1
1Department of Urology, The First Affiliated Hospital of Soochow University, 188 Shizi Road, Suzhou, China.
Abstract:
Pyroptosis, a form of programmed cell death distinct from apoptosis and necrosis, is thought to be closely associated with the pathogenesis of diseases. Recently, the association between pyroptosis and urinary diseases has attracted considerable attention, and a comprehensive review focusing on this issue is not available. In this study, we reviewed the role of pyroptosis in the development and progression of benign urinary diseases and urinary malignancies. Based on this, pyroptosis has been implicated in the development of urinary diseases. In summary, this review sheds light on future research directions and provides novel ideas for using pyroptosis as a powerful tool to fight urinary diseases.
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