Related Experiment Video

Updated: Jul 8, 2025

Modeling Charcot-Marie-Tooth Disease In Vitro by Transfecting Mouse Primary Motoneurons
07:43

Modeling Charcot-Marie-Tooth Disease In Vitro by Transfecting Mouse Primary Motoneurons

Published on: January 7, 2019

7.0K

Targeting muscle to treat Charcot-Marie-Tooth disease

David Villarroel-Campos1,2, James N Sleigh1,2

  • 1Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, UK.

Neural Regeneration Research
|December 16, 2023
PubMed
Abstract

No abstract available in PubMed .

More Related Videos

Systemic Delivery of MicroRNA Using Recombinant Adeno-associated Virus Serotype 9 to Treat Neuromuscular Diseases in Rodents
06:51

Systemic Delivery of MicroRNA Using Recombinant Adeno-associated Virus Serotype 9 to Treat Neuromuscular Diseases in Rodents

Published on: August 10, 2018

7.7K
Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain
03:26

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain

Published on: March 8, 2024

2.7K

Related Experiment Videos

Last Updated: Jul 8, 2025

Modeling Charcot-Marie-Tooth Disease In Vitro by Transfecting Mouse Primary Motoneurons
07:43

Modeling Charcot-Marie-Tooth Disease In Vitro by Transfecting Mouse Primary Motoneurons

Published on: January 7, 2019

7.0K
Systemic Delivery of MicroRNA Using Recombinant Adeno-associated Virus Serotype 9 to Treat Neuromuscular Diseases in Rodents
06:51

Systemic Delivery of MicroRNA Using Recombinant Adeno-associated Virus Serotype 9 to Treat Neuromuscular Diseases in Rodents

Published on: August 10, 2018

7.7K
Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain
03:26

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain

Published on: March 8, 2024

2.7K

Related Concept Videos

Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

1.5K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
1.5K
Satellite Stem Cells and Muscular Dystrophy01:21

Satellite Stem Cells and Muscular Dystrophy

2.0K
Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...
2.0K

Articles linked to this work by shared authors, journal, and citation graph.

The neuropathy-causing GARS1 ΔETAQ mutation drives pathology in subsets of motor and sensory neurons in mice.

bioRxiv : the preprint server for biology·2026

Junctions in Jeopardy: the neuromuscular junction is a selective pathological target in Charcot-Marie-Tooth disease.

Mammalian genome : official journal of the International Mammalian Genome Society·2026

Brain-derived neurotrophic factor coordinates neuron-intrinsic programs to enhance axonal regeneration in human motor neurons.

Science signaling·2026

Disruption of BDNF signalling in neuropathologies.

Biochemical Society transactions·2026

TBK1 activity regulates the directionality of axonal transport of signalling endosomes.

Life science alliance·2026

Gene-Pseudogene Inversions as a Hidden Source of Missing Heritability.

medRxiv : the preprint server for health sciences·2025

Basic principles for astrocyte-to-neuron conversion.

Neural regeneration research·2026

Axonal pathology and impaired axo-glial crosstalk as early drivers of neurodegeneration.

Neural regeneration research·2026

Gut-to-brain signaling: New frontiers in treating brain disorders.

Neural regeneration research·2026

Lycium barbarum glycopeptide protects against inherited retinal degeneration in rd10 mice by regulating phototransduction and neuroinflammatory pathways.

Neural regeneration research·2026

Exosomes enriched with microRNA mimics or inhibitors: A possible treatment modality for diabetic retinopathy.

Neural regeneration research·2026

Exosome research and neuroimaging techniques: Visualization analysis of development trends and research hotspots.

Neural regeneration research·2026

Awareness, Knowledge, and Attitudes of Dentists in Türkiye Regarding the 2034 Phase-Out of Dental Amalgam Under the Minamata Convention: A Cross-Sectional Study.

Oral health & preventive dentistry·2026

Dental Anxiety Before Non-Surgical Periodontal Treatment: Evaluating the Interaction of Gender and Education Level.

Oral health & preventive dentistry·2026

Fluoride Toothpaste Market Surveillance in the Dominican Republic: Quality Gaps and Policy Implications.

Oral health & preventive dentistry·2026

Dequalinium chloride promotes the killing efficacy of aminoglycoside antibiotics against Pseudomonas aeruginosa by enhancing membrane potential.

Microbiology spectrum·2026

The Expression of Neuropeptides in Pulpitis: A Systematic Review and Meta-Analysis.

International endodontic journal·2026

Tooth Discoloration Potential of Coffee With Common Additives and the Effectiveness of Whitening Toothpastes in Stain Removal.

International journal of dental hygiene·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us