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Millimetric devices for nerve stimulation: a promising path towards miniaturization.
Ryan M Dorrian1, Anna V Leonard1, Antonio Lauto2
1Spinal Cord Injury Research Group, School of Biomedicine, The University of Adelaide, Adelaide, SA, Australia.
Neural Regeneration Research
|December 16, 2023
Summary
Researchers have developed tiny, millimetric nerve stimulation devices, overcoming challenges of size and power for less invasive treatments. These advancements pave the way for broader therapeutic applications in various medical conditions.
Area of Science:
- Biomedical Engineering
- Neuroscience
- Materials Science
Background:
- Nerve stimulation offers therapeutic benefits for various conditions.
- Current devices are large, complex, and require invasive implantation.
- Device miniaturization is crucial for broader clinical adoption and reduced invasiveness.
Purpose of the Study:
- To review recent advancements in millimetric-sized nerve stimulation devices.
- To highlight engineering solutions for device miniaturization.
- To discuss potential future applications and considerations.
Main Methods:
- Review of research on millimetric nerve stimulation devices.
- Analysis of designs utilizing antennas, mini-coils, and advanced materials.
- Examination of power reception methods including ultrasound.
Main Results:
- Several groups have successfully developed millimetric nerve stimulation devices.
- Key design elements and enabling technologies have been identified.
- Pilot studies show promise for these miniaturized devices.
Conclusions:
- Millimetric nerve stimulation devices represent a significant breakthrough in neuromodulation.
- These devices overcome limitations of current technologies, enabling less invasive interventions.
- Further research and development will expand their therapeutic potential.
