Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Role of Hippocampus in Memory01:19

Role of Hippocampus in Memory

264
The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
264
Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

446
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
446
Reason and Intuition01:37

Reason and Intuition

6.5K
The human brain processes information for decision-making using one of two routes: an intuitive system and a rational system (Epstein, 1994; popularized by Kahneman, 2011 as System 1 and System 2, respectively). The intuitive system is quick, impulsive, and operates with minimal effort, relying on emotions or habits to provide cues for what to do next, while the rational system is logical, analytical, deliberate, and methodical. Research in neuropsychology suggests that the...
6.5K
Storage01:23

Storage

86
A schema is a mental framework that helps individuals organize and interpret information. Schemata, formed from previous experiences, influence how we process new information: how we encode it, the inferences we make, and how we retrieve it. For instance, a schema for what a typical classroom looks like might include desks, a teacher's desk, a whiteboard, and students in such an environment. This expectation helps us quickly understand and navigate new classrooms without needing to analyze...
86

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Distinct aging-related profiles of allocentric knowledge recall following navigation in an immersive, naturalistic, city-like environment.

Frontiers in aging neuroscience·2026
Same author

"The architecture of curiosity: How spatial configuration influences affect, exploration, and memory".

Neuropsychologia·2026
Same author

Reply to a Letter to the Editor Regarding "Genetic Risk Scores, Perceived Neighborhood Disorder, and Sleep Duration".

Sleep·2026
Same author

Differential representations of spatial environments in mPFC and hippocampus underpinning flexible navigation.

NeuroImage·2026
Same author

Genetic risk scores, perceived neighborhood disorder, and sleep duration.

Sleep·2026
Same author

Prevalence of Helicobacter pylori infection in the general population in Wuzhou, China: a cross-sectional study.

Infectious agents and cancer·2025

Related Experiment Video

Updated: Jul 8, 2025

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function
06:17

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Published on: January 26, 2024

2.0K

The neural correlates of memory integration in value-based decision-making during human spatial navigation.

Qiliang He1, Jancy Ling Liu2, Lou Eschapasse1

  • 1School of Psychology, Georgia Institute of Technology, USA.

Neuropsychologia
|December 16, 2023
PubMed
Summary

This study reveals how the brain values navigation choices by integrating spatial memory. Different brain regions, including the prefrontal cortex, are involved depending on task demands.

Keywords:
Decision-makingMemory integrationSpatial navigationfMRI

More Related Videos

Modeling the Functional Network for Spatial Navigation in the Human Brain
05:55

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

1.1K
Virtual Reality Experiments with Physiological Measures
07:09

Virtual Reality Experiments with Physiological Measures

Published on: August 29, 2018

12.8K

Related Experiment Videos

Last Updated: Jul 8, 2025

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function
06:17

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Published on: January 26, 2024

2.0K
Modeling the Functional Network for Spatial Navigation in the Human Brain
05:55

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

1.1K
Virtual Reality Experiments with Physiological Measures
07:09

Virtual Reality Experiments with Physiological Measures

Published on: August 29, 2018

12.8K

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Decision-Making

Background:

  • Value-based decision-making relies on memory integration and segmentation.
  • Neural correlates of decision-making are well-studied, but less so for spatial navigation and memory.
  • Prior research has explored computational models of memory and decision-making.

Purpose of the Study:

  • Investigate neural substrates of decisions involving segmentation or integration of wayfinding outcomes.
  • Examine how different spatial navigation task demands influence value-based decision-making.
  • Identify brain regions involved in estimating the value of navigational choices.

Main Methods:

  • Virtual spatial navigation tasks with varying demands.
  • Computational modeling of memory and decision-making.
  • Neuroimaging techniques to measure neural activity (implied).

Main Results:

  • Estimated value (EV) modulated activity in dorsomedial prefrontal (dmPFC) and ventrolateral prefrontal (vlPFC) cortex when spatial distance computation and self-navigation ability evaluation were required.
  • Superior parietal cortex tracked EV when only spatial distance memory was needed, without self-navigation ability evaluation.
  • Divergent neural substrates were identified for memory integration in value-based decision-making based on spatial processing demands.

Conclusions:

  • Neural mechanisms for value-based decision-making in spatial navigation differ based on cognitive load and memory demands.
  • Prefrontal cortex plays a key role in decisions requiring complex spatial memory evaluation.
  • Parietal cortex is involved in simpler spatial memory-based value estimations.