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Updated: Jul 8, 2025

Preparation of Agar Bead Embedded Mycobacterium abscessus to Inoculate Immunocompetent Mice Intratracheally
Published on: April 25, 2025
Pulmonary Mycobacterium abscessus infection treated in combination with inhaled tigecycline
Andreas Arnholdt Pedersen1,2,3, Andreas Fløe4, Anders Løkke5,2
1Department of Pulmonary Research, Lillebaelt Hospital, Vejle, Denmark Andreas.Arnholdt.Pedersen@rsyd.dk.
Abstract:
Pulmonary disease caused by Mycobacterium abscessus is difficult to treat, as there is currently no reliable evidence-based treatment. Treatment is long, complex and has many side effects. In this case, we report a patient with treatment-refractory pulmonary M abscessus disease, treated with inhaled tigecycline. Treatment with inhaled tigecycline lasted 15 months with comparably limited side effects. There were no positive mycobacterial cultures in the follow-up period of 2 years. Inhaled tigecycline is an option in the treatment of pulmonary M. abscessus when first-line treatment fails. Additional research should investigate this further.
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