Related Experiment Video
Updated: Jul 8, 2025

Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness
Published on: December 6, 2024
A compressed large language model embedding dataset of ICD 10 CM descriptions
Michael J Kane1, Casey King2,3, Denise Esserman4
1Department of Biostatistics, School of Public Health, Yale University, New Haven, USA. michael.kane@yale.edu.
Novel datasets represent International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM) codes numerically. These embeddings capture relationships and context, enhancing machine learning for biomedical informatics research.
Area of Science:
- Biomedical Informatics
- Machine Learning
- Natural Language Processing
Background:
- International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM) codes are essential for healthcare but lack inherent numerical representation for advanced analysis.
- Existing methods for utilizing ICD-10-CM codes in machine learning are limited by their discrete nature and lack of contextual information.
Purpose of the Study:
- To generate novel datasets of numerical representations for ICD-10-CM codes.
- To create informative input features for machine learning models by capturing semantic relationships and context.
- To enable more advanced analyses in biomedical informatics using readily available datasets.
Main Methods:
- Utilized a large language model to generate description embeddings for ICD-10-CM codes.
- Applied dimension reduction via an autoencoder to compress the embeddings.
- Validated the dimension reduction using the autoencoder and a supervised model for hierarchical category estimation.
Main Results:
- Successfully reduced the dimensionality of ICD-10-CM code embeddings to as few as 10 dimensions.
- Maintained the ability to reproduce original embeddings with high fidelity at reduced dimensions.
- Provided multiple compression levels for user-selectable requirements.
Conclusions:
- The generated numerical datasets of ICD-10-CM codes significantly enhance their utility in biomedical informatics.
- This approach facilitates more advanced machine learning applications by providing context-aware, dimension-reduced features.
- The readily available datasets require no additional setup, promoting wider adoption and research.
More Related Videos
07:50A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
06:09P300-Based Brain-Computer Interface Speller Performance Estimation with Classifier-Based Latency Estimation
Published on: September 8, 2023
Related Concept Videos
Classification of Illness
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
Stereotype Content Model
Diagnostic and Statistical Manual of Mental Disorders (DSM)
How Data are Classified: Categorical Data
Data are classified based on whether they are measurable or not. Categorical data cannot be measured; instead, it can be divided into categories. For example, if Y denotes a person's party affiliation, some examples of Y include...
Anatomical Terminology
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.