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Adile Orhan1,2, Sara Mørup1, Laurids Østergaard Poulsen3

  • 1Center for Surgical Science, Kirurgisk Afdeling, Sjællands Universitetshospital, Køge.

Ugeskrift for Laeger
|December 18, 2023
PubMed
Summary

Immunotherapy shows promise for colorectal cancer (CRC), particularly for mismatch-repair deficient (dMMR) metastatic CRC. Pre-operative immunotherapy yields high response rates in dMMR CRC patients, with ongoing research into new combinations.

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Area of Science:

  • Oncology
  • Gastroenterology
  • Immunology

Background:

  • Colorectal cancer (CRC) affects approximately 4,500 individuals annually in Denmark.
  • Current immunotherapy indications for CRC are limited to specific patient subgroups.

Conclusions:

  • Immunotherapy is an emerging and effective treatment for a subset of colorectal cancer patients.
  • Further research into immunotherapy combinations is crucial for expanding its application in CRC.

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