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Implementing a Pharmacogenomic-driven Algorithm to Guide Antiplatelet Therapy among Caribbean Hispanics: A

Héctor Nuñez-Medina1, Mariangeli Monero2, Lorna M Torres1

  • 1Division of Cardiovascular Medicine, University of Puerto Rico - Medical Sciences Campus, School of Medicine, San Juan, Puerto Rico, United States.

Medrxiv : the Preprint Server for Health Sciences
|December 18, 2023
PubMed
Summary

Genotype-guided antiplatelet therapy reduced cardiovascular events in Caribbean Hispanic patients after coronary stenting. This pharmacogenomic approach using a clinical decision support algorithm improved outcomes compared to standard care.

Keywords:
Adverse Cardiovascular and Cerebrovascular EventsAntiplatelet TherapyCardiovascular DiseasesCaribbean HispanicsClinical Decision Support ToolClopidogrelPharmacogenomicsPolygenic Risk Factor

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