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The Utility of Salvage Radiotherapy for an Inoperable Inguinal Recurrence of Squamous Cell Carcinoma of the Penis
W C Ian Janes1, Paul Johnston2, Michael Organ2
1Medicine, Memorial University of Newfoundland, St. John's, CAN.
Abstract:
Penile cancer is a rare genitourinary malignancy for which limited treatment options exist beyond primary surgical resection. Metastatic lymphadenopathy represents a particularly poor prognosis with a lack of literature to suggest the effectiveness of radiation or systemic therapies. Our case documents an inguinal recurrence of penile squamous cell carcinoma not amenable to surgical intervention demonstrating complete response to salvage radiotherapy in the palliative setting. These observations propose the need for further research around the utility of radiotherapy in the management of metastatic penile malignancies.
Insights
Salvage radiotherapy achieved a complete response in a penile cancer recurrence, offering a palliative option when surgery is not feasible. This suggests further research into radiotherapy for metastatic penile cancer management is warranted.
Area of Science:
- Oncology
- Genitourinary Malignancies
- Radiation Oncology
Background:
- Penile cancer is a rare malignancy with limited treatment options, especially for metastatic disease.
- Metastatic lymphadenopathy in penile cancer carries a poor prognosis, with limited evidence on radiation or systemic therapy efficacy.
- Surgical resection is the primary treatment, but recurrence can limit further surgical intervention.
