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Pain Management in Osteoporosis.

Rajesh Kumar Rajnish1, Abhay Elhence1, S S Jha2

  • 1Department of Orthopaedics, All India Institute of Medical Sciences, India Jodhpur.

Indian Journal of Orthopaedics
|December 18, 2023
PubMed
Summary
This summary is machine-generated.

Osteoporosis causes bone loss and fractures, leading to pain in older adults. Effective pain management requires a multifaceted approach beyond basic medications.

Keywords:
Chronic painFragility fractureOsteoporosisOsteoporotic fractureOsteoporotic pain treatment

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Area of Science:

  • Gerontology
  • Orthopedics
  • Pharmacology

Background:

  • Osteoporosis is a prevalent metabolic bone disease characterized by reduced bone mineral density and microstructural changes, increasing fracture risk.
  • Fragility fractures in elderly patients with osteoporosis often cause significant acute or chronic pain, frequently accompanied by comorbidities.
  • Current antiresorptive therapies offer only partial pain relief, necessitating additional analgesic strategies.

Purpose of the Study:

  • To review the etiology and mechanisms of pain in osteoporotic patients.
  • To discuss current and potential pain management strategies for osteoporosis-related pain.
  • To highlight the need for a comprehensive approach to managing pain in this population.

Main Methods:

  • Literature review of osteoporosis, pain mechanisms, and analgesic therapies.
  • Analysis of pharmacological treatments including NSAIDs, COX-2 inhibitors, and opioids.
  • Consideration of nonpharmacological and surgical interventions.

Main Results:

  • Osteoporotic fractures are a major source of pain, particularly in the elderly.
  • NSAIDs and COX-2 inhibitors may manage acute pain, but neuropathic pain is challenging.
  • Opioids can address pain but carry risks; a multimodal strategy is essential.

Conclusions:

  • Pain management in osteoporosis requires a comprehensive strategy.
  • This includes pharmacological, nonpharmacological, and, in select cases, surgical interventions.
  • Addressing the multifaceted nature of pain is crucial for improving patient outcomes.