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Glycosylated haemoglobin and blood glucose levels in Libyan diabetic patients
Insights
This study on 178 Libyan men found poorly controlled diabetes, with high glycosylated hemoglobin (HbA1) and blood glucose levels. Obesity was common in older patients, highlighting the link between diabetes and weight management.
Area of Science:
- Endocrinology
- Metabolic Diseases
- Clinical Chemistry
Background:
- Diabetes mellitus is a significant global health concern.
- Glycosylated hemoglobin (HbA1) and fasting blood glucose are key indicators of glycemic control.
- Understanding diabetes prevalence and control in specific populations is crucial for public health.
Purpose of the Study:
- To assess glycosylated hemoglobin (HbA1) and fasting blood glucose levels in Libyan diabetic men.
- To investigate the relationship between these glycemic markers and patient demographics, including age and obesity.
- To evaluate the level of diabetes control within the study cohort.
Main Methods:
- Cross-sectional study involving 178 Libyan diabetic men.
- Measurement of glycosylated hemoglobin (HbA1) and fasting blood glucose levels.
- Statistical analysis to determine correlations between glycemic markers, age, obesity, and duration of diabetes.
Main Results:
- Mean HbA1 was 11.5% +/- 0.4% and mean fasting blood glucose was 236 +/- 7 mg/dL.
- A significant positive correlation was observed between fasting blood glucose and HbA1 (r = 0.37; P < 0.001).
- Poor diabetes control was indicated by the correlation between HbA1 and diabetes duration; obesity was prevalent in the 51-60 age group.
Conclusions:
- Libyan diabetic men in this cohort exhibit poorly controlled diabetes.
- Glycosylated hemoglobin (HbA1) is a valuable tool for assessing long-term glycemic control in epidemiological studies.
- Further research into diabetes management strategies for this population is warranted.
Abstract:
Glycosylated haemoglobin (HbA1) and fasting blood glucose levels of 178 Libyan diabetic men were determined. The mean levels respectively were 11.5 +/- 0.4% and 236 +/- 7 mg.dl-1. In this study group, there were 78 patients with insulin-dependent diabetes and 100 with non-insulin-dependent diabetes. The highest percentage of patients belong to the age group 51-60 with the onset of diabetes between 41 and 50 years of age. The highest number of obese patients were in the age group 51-60 indicating the strong association between diabetes and obesity. A statistically significant correlation was found between fasting blood glucose levels and HbA1 concentrations (r = 0.37; P less than 0.001). Correlations between urinary glucose and HbA1 or fasting blood glucose were highly significant. These diabetic patients have a poorly controlled diabetes as indicated by the correlation between HbA1 and duration of diabetes. There was no significant difference in HbA1 levels of patients undergoing insulin administration and those taking oral hypoglycaemic drugs. Glycosylated haemoglobin levels will be a valuable adjunct to blood glucose determinations in epidemiological studies.