Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

71
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
71
Esophageal Varices-I: Introduction01:24

Esophageal Varices-I: Introduction

149
Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
149
Disorders of Hemostasis01:24

Disorders of Hemostasis

922
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
922
Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

272
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
272
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

188
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
188
Peptic Ulcer Disease I: Introduction01:30

Peptic Ulcer Disease I: Introduction

176
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
176

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Integrated Psychosomatic Care in General Hospital Medicine: An Observational Study of Outcomes in Medically Complex Inpatients.

Journal of the Academy of Consultation-Liaison Psychiatry·2026
Same author

Proactive consultation-liaison-services (CL): comparing PHQ-4 screening with traditional referral pathways in medical inpatients - a prospective comparative pilot study.

BMC psychiatry·2026
Same author

Clinical and genomic profiling of <i>Klebsiella pneumoniae</i> in liver abscesses.

Virulence·2026
Same author

Intraductal cryobiopsy via percutaneous cholangioscopy for biliary strictures: a multicenter feasibility study.

Endoscopy·2025
Same author

[Staffing situation and basics requirement calculations in the inpatient and outpatient sector in Germany - a representative survey by the Working Group of Senior Gastroenterology Hospital Physicians (ALGK)].

Zeitschrift fur Gastroenterologie·2024
Same author

Response.

Gastrointestinal endoscopy·2024
Same journal

Effect of anticholinergic burden on cardiac functions in older patients.

Zeitschrift fur Gerontologie und Geriatrie·2026
Same journal

[Communication in later life under institutional conditions : Professional perspectives on communication of ageing people with profound intellectual and multiple disabilities].

Zeitschrift fur Gerontologie und Geriatrie·2026
Same journal

Zeitschrift fur Gerontologie und Geriatrie·2026
Same journal

Zeitschrift fur Gerontologie und Geriatrie·2026
Same journal

Zeitschrift fur Gerontologie und Geriatrie·2026
Same journal

Zeitschrift fur Gerontologie und Geriatrie·2026
See all related articles

Related Experiment Video

Updated: Jul 8, 2025

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
04:09

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices

Published on: June 13, 2025

187

[Gastrointestinal bleeding in old age].

Guntje Kneiseler1, Alexander Dechêne2

  • 1Medizinische Klinik 6 (Schwerpunkte Gastroenterologie, Hepatologie, Endokrinologie und Ernährungsmedizin) am Klinikum Nürnberg, Universitätsklinik der Paracelsus Medizinischen Privatuniversität Nürnberg, Prof.-Ernst-Nathan-Str. 1, 90419, Nürnberg, Deutschland.

Zeitschrift Fur Gerontologie Und Geriatrie
|December 18, 2023
PubMed
Summary
This summary is machine-generated.

Gastrointestinal bleeding, a common ailment influenced by age, requires careful management. This article details pre-endoscopic strategies for upper and lower bleeding, emphasizing risk assessment and treatment.

Keywords:
Blood transfusionDiverticular bleedingEndoscopyGastrointestinal tractPeptic ulcer disease

More Related Videos

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors
03:05

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors

Published on: February 16, 2024

1.1K
Laparoscopic Splenectomy with Pericardial Devascularization for Hypersplenism and Esophageal Variceal Hemorrhage Due to Portal Hypertension
04:00

Laparoscopic Splenectomy with Pericardial Devascularization for Hypersplenism and Esophageal Variceal Hemorrhage Due to Portal Hypertension

Published on: November 15, 2024

176

Related Experiment Videos

Last Updated: Jul 8, 2025

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
04:09

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices

Published on: June 13, 2025

187
Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors
03:05

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors

Published on: February 16, 2024

1.1K
Laparoscopic Splenectomy with Pericardial Devascularization for Hypersplenism and Esophageal Variceal Hemorrhage Due to Portal Hypertension
04:00

Laparoscopic Splenectomy with Pericardial Devascularization for Hypersplenism and Esophageal Variceal Hemorrhage Due to Portal Hypertension

Published on: November 15, 2024

176

Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Clinical Management

Context:

  • Gastrointestinal bleeding is a frequent clinical presentation, with advanced age as a significant risk factor.
  • Symptomatology and management strategies for gastrointestinal bleeding vary based on the bleeding source (upper, middle, or lower GI tract).
  • Existing German and international clinical guidelines provide frameworks for preclinical and clinical management.

Purpose:

  • To elucidate the clinical presentation and management of upper and lower gastrointestinal bleeding.
  • To focus on pre-endoscopic management, including risk stratification, transfusion protocols, coagulation management, and initial pharmacological interventions for nonvariceal and variceal bleeding.
  • To highlight recent advancements in endoscopic and interventional therapies for gastrointestinal bleeding.

Summary:

  • This article details the pre-endoscopic management of upper gastrointestinal bleeding, differentiating between nonvariceal and variceal causes.
  • Key aspects covered include risk stratification, transfusion and coagulation management, and initial pharmacological treatments.
  • Current developments in endoscopic and interventional treatments are also discussed, providing a comprehensive overview.

Impact:

  • Provides clinicians with updated information on managing gastrointestinal bleeding, particularly focusing on pre-endoscopic strategies.
  • Aims to improve patient outcomes by outlining evidence-based approaches to risk assessment and treatment initiation.
  • Highlights the evolving landscape of endoscopic and interventional therapies, guiding future clinical practice.