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Cardiometabolic-related dietary patterns and thyroid function: a population-based cross-sectional study.
Nazanin Moslehi1, Saba Mohammadpour2, Parvin Mirmiran3
1Nutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, No. 24, Shahid Arabi St, Yemen Blvd, Chamran Exp, Tehran, 1985717413, Iran. moslehinazanin@yahoo.com.
European Journal of Medical Research
|December 19, 2023
Summary
A diet high in fast foods and soft drinks, and low in confectionery, is linked to increased thyroid-stimulating hormone (TSH) levels and a higher risk of subclinical hypothyroidism.
Area of Science:
- Endocrinology
- Nutritional Science
- Epidemiology
Background:
- Thyroid function and cardiometabolic health are interconnected.
- Limited understanding exists regarding the association between dietary patterns and thyroid function.
Purpose of the Study:
- To investigate the relationship between cardiometabolic-related dietary patterns and thyroid function.
- To examine associations with thyroid-stimulating hormone (TSH), free thyroxine, and thyroid peroxidase antibody (TPOAb).
Main Methods:
- Cross-sectional study of 3520 participants in the Tehran Lipid and Glucose Study.
- Reduced rank regression identified dietary patterns based on food groups.
- Linear and logistic regression analyzed associations with thyroid function and dysfunction.
Main Results:
- Two identified dietary patterns were associated with elevated TSH levels in euthyroid individuals.
- Higher intake of fast foods, soft drinks, and legumes correlated with increased odds of subclinical hypothyroidism.
- No significant associations were found with hyperthyroidism or TPOAb positivity.
Conclusions:
- A dietary pattern characterized by high fast food, soft drink, and legume consumption, and low intake of confectionery, is associated with higher TSH and increased odds of subclinical hypothyroidism.
- Dietary choices may play a role in thyroid health, particularly in relation to subclinical hypothyroidism.
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