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Published on: September 28, 2022
A Mechanistic Model for Long COVID Dynamics
Jacob Derrick1, Ben Patterson1, Jie Bai2
1Department of Mathematics, University of Tennessee at Chattanooga, Chattanooga, TN 37403, USA.
Abstract:
Long COVID, a long-lasting disorder following an acute infection of COVID-19, represents a significant public health burden at present. In this paper, we propose a new mechanistic model based on differential equations to investigate the population dynamics of long COVID. By connecting long COVID with acute infection at the population level, our modeling framework emphasizes the interplay between COVID-19 transmission, vaccination, and long COVID dynamics. We conducted a detailed mathematical analysis of the model. We also validated the model using numerical simulation with real data from the US state of Tennessee and the UK.
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