Childhood BMI trajectories predict cardiometabolic risk and perceived stress at age 13 years: the STARS cohort

Yun Chen1, Frida Dangardt2,3, Lars Gelander4

  • 1School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

PubMed

Insights

Children with excessive weight gain trajectories from birth are at higher risk for cardiometabolic issues and stress by age 13. Early BMI gain significantly impacts adolescent health outcomes.

Area of Science:

  • Pediatric Health
  • Cardiovascular Health
  • Public Health

Background:

  • Childhood Body Mass Index (BMI) trajectories are critical indicators of future health.
  • Understanding the long-term impact of early-life BMI on adolescent health is essential for preventative strategies.

Purpose of the Study:

  • To analyze Body Mass Index (BMI) trajectories from birth through childhood.
  • To investigate the association between these BMI trajectories and health outcomes at age 13.
  • To determine the critical time windows during which early-life BMI influences adolescent health.

Main Methods:

  • Group-based trajectory modeling was used to analyze retrospective weight and height data from birth.
  • Linear regression assessed associations between BMI trajectories and health outcomes at age 13.
  • Health outcomes included waist circumference (WC), systolic blood pressure (SBP), psychosomatic symptoms, and perceived stress.

Main Results:

  • Three distinct BMI trajectories were identified: normal, moderate, and excessive gain.
  • Adolescents with excessive BMI gain exhibited significantly higher WC, SBP, white blood cell counts (WBC), and stress levels at age 13 compared to normal gain.
  • The association between early-life BMI and SBP emerged around age 6 for the excessive gain group, versus age 12 for normal and moderate gain groups.

Conclusions:

  • An excessive BMI gain trajectory from birth is a predictor of cardiometabolic risk and stress in adolescents.
  • Early identification and management of excessive BMI gain are crucial for mitigating long-term health risks.
  • The timing of BMI changes in early life has a differential impact on adolescent cardiovascular health.
Abstract

Related Concept Videos

Nature and Nurture01:10

Nature and Nurture

Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience,...
20.5K
Introduction to Stress and Lifestyle01:27

Introduction to Stress and Lifestyle

Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
115
Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
31
Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
29
Stress Prevention and Stress Management Techniques I01:26

Stress Prevention and Stress Management Techniques I

Stress prevention and management are crucial for maintaining well-being and building resilience. Techniques to manage stress include cultivating qualities like conscientiousness, a sense of personal control, and self-efficacy. Each of these traits significantly reduces stress and promotes healthier lifestyle choices and outcomes.
Conscientiousness
Conscientious individuals tend to be organized, responsible, and disciplined. They prioritize completing tasks and following structured routines,...
50
Stress Prevention and Stress Management Techniques IV01:26

Stress Prevention and Stress Management Techniques IV

Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
29