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ICTV Virus Taxonomy Profile: Wupedeviridae 2023
Jens H Kuhn1, Scott Adkins2, Katherine Brown3
1Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick MD 21702, USA.
The Wupedeviridae family comprises negative-sense RNA viruses discovered in myriapods. Their genome structure includes genes for nucleoprotein, glycoprotein, and RNA-directed RNA polymerase.
Area of Science:
- Virology
- Myriapod Biology
- RNA Virus Taxonomy
Background:
- Wupedeviridae represents a family of negative-sense RNA viruses.
- These viruses have been identified in myriapods, a group of arthropods.
Purpose of the Study:
- To summarize the International Committee on Taxonomy of Viruses (ICTV) report on the Wupedeviridae family.
- To provide an overview of the genomic characteristics and taxonomic classification of Wupedeviridae.
Main Methods:
- Review and summarization of the official ICTV report.
- Analysis of genomic data including genome size and open reading frames (ORFs).
Main Results:
- Wupedeviridae genomes are approximately 20.5 kb in size.
- The genome consists of three monocistronic RNA segments.
- Encoded proteins include nucleoprotein (NP), glycoprotein (GP), and a large (L) protein with an RNA-directed RNA polymerase (RdRP) domain.
Conclusions:
- The ICTV has formally classified Wupedeviridae as a distinct viral family.
- The genomic organization provides insights into the replication and evolution of these myriapod-infecting viruses.
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