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ICTV Virus Taxonomy Profile: Cruliviridae 2023
Jens H Kuhn1, Scott Adkins2, Katherine Brown3
1Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick MD 21702, USA.
The Journal of General Virology
|December 20, 2023
Summary
Cruliviridae are negative-sense RNA viruses found in crustaceans. This summary details their genome structure and protein-coding genes, based on the ICTV report.
Area of Science:
- Virology
- Invertebrate Pathology
Background:
- Crustaceans harbor diverse viruses, including the recently classified Cruliviridae family.
- Cruliviridae possess negative-sense RNA genomes, a characteristic shared by many significant viral pathogens.
Purpose of the Study:
- To summarize the International Committee on Taxonomy of Viruses (ICTV) report on the Cruliviridae family.
- To provide an overview of the genomic and proteomic characteristics of Cruliviridae.
Main Methods:
- Analysis of the ICTV report on Cruliviridae taxonomy and classification.
- Review of genomic data for Cruliviridae, focusing on RNA segments and open reading frames (ORFs).
Main Results:
- Cruliviridae genomes are 10.8–11.5 kb and composed of three RNA segments.
- ORFs encode essential viral proteins: nucleoprotein (NP), glycoprotein (GP), and RNA-directed RNA polymerase (RdRP) within the large (L) protein.
- Some Cruliviridae members also encode a zinc-finger (Z) protein of currently unknown function.
Conclusions:
- The Cruliviridae family represents a distinct group of RNA viruses infecting crustaceans.
- Understanding the genomic makeup of Cruliviridae is crucial for crustacean health and viral research.
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