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Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
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Author Spotlight: Advancing Syphilis Research — Innovations in Treponema pallidum Cultivation and Genetic Engineering
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[Syphilis: uncommon presentation forms].

Emilse D Díaz Lobo1, Rocío I Piña1, Anaclara Murujosa1

  • 1Servicio de Clínica Médica, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.

Medicina
|December 20, 2023
PubMed
Summary

Uncommon syphilis forms like neurosyphilis, otosyphilis, and ocular syphilis present diverse symptoms. Early diagnosis and antibiotic treatment, primarily penicillin G, are crucial for managing these challenging infections.

Area of Science:

  • Infectious Diseases
  • Neurology
  • Ophthalmology
  • Otolaryngology
Keywords:
central nervous system syphilisgeneral paresisneurosyphilissyphilitic meningitistabes dorsalis

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Background:

  • Syphilis, caused by Treponema pallidum, can manifest in rare forms affecting the nervous system (neurosyphilis), eyes (ocular syphilis), and ears (otosyphilis).
  • These conditions often present with varied and sometimes subtle clinical signs, making diagnosis difficult.
  • Despite diagnostic challenges, prompt antibiotic intervention can lead to reversible outcomes.