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Left ventricular derived cardiac output.

W J French, R J Haskell, R W Knouse

    The American Journal of Cardiology
    |January 1, 1987
    PubMed
    Summary
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    Cardiac output (CO) can now be accurately measured using left ventricular (LV) injection of indocyanine green dye. This method offers a simpler alternative to traditional right-sided cardiac catheterization for CO determination.

    Area of Science:

    • Cardiology
    • Medical Imaging
    • Physiology

    Background:

    • Right-sided cardiac catheterization is the standard for measuring cardiac output (CO).
    • Left-sided cardiac catheterization is more common in suspected coronary artery disease, often omitting CO measurement.
    • There is a need for a less invasive method to measure CO.

    Purpose of the Study:

    • To determine if cardiac output (CO) can be accurately measured from the left side of the heart.
    • To evaluate the efficacy of indocyanine green dye injection into the left ventricle (LV) for CO measurement.

    Main Methods:

    • 24 patients undergoing cardiac catheterization were studied.
    • Near-simultaneous determination of CO using indocyanine green dye injected into the pulmonary artery and the LV cavity.

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  • Comparison of CO measurements derived from both injection sites.

    • Main Results:

    • Close agreement was found between pulmonary artery and LV-derived cardiac outputs (Pulmonary artery = 0.93 LV + 0.12).
    • Pulmonary artery derived CO averaged 5.7 ± 2.0 L/min; LV derived CO averaged 6.1 ± 2.2 L/min.
    • Pulmonary artery and LV derived stroke volumes showed a close relation (82 ± 33 ml vs. 86 ± 36 ml).

    Conclusions:

    • Cardiac output can be accurately measured by injecting indocyanine green dye into the left ventricular cavity.
    • This provides a viable alternative for CO assessment, potentially simplifying cardiac catheterization procedures.