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Spatial Multiobjective Optimization of Agricultural Conservation Practices using a SWAT Model and an Evolutionary Algorithm
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Balancing competing objectives in bigel formulations using many-objective optimization algorithms and different

Mohamed Kouider Amar1, Soufiane Rahal2, Maamar Laidi3

  • 1Biomaterials and Transport Phenomena Laboratory (LBMPT), University Dr., Yahia Fares of Medea, Medea 26000, Algeria; Department of Process Engineering, Institute of Technology, University Dr., Yahia Fares of Medea, Medea 26000, Algeria; Laboratory of Quality Control, Physico-Chemical Department, SAIDAL of Medea, Medea 26000, Algeria; Faculty of Technology, University Dr., Yahia Fares of Medea, Medea 26000, Algeria.

European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V
|December 20, 2023
PubMed
Summary

This study optimized bigel systems using many-objective optimization (MaOEAs) to balance conflicting properties like microstructural characteristics, stability, and drug release. The RSM-RVEA approach demonstrated effective convergence for complex formulation challenges.

Keywords:
BigelsDecision-making methodsDrug deliveryMany-objective optimization algorithmsResponse surface methodologyRheology

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