Related Experiment Videos
Is gastroesophageal reflux a factor in some asthmatics?
The American Journal of Gastroenterology
|February 1, 1987
Summary
Antireflux surgery significantly improved asthma symptoms in adults with both conditions. Many patients reduced or stopped asthma medications after the procedure, showing a strong link between GER and respiratory issues.
Area of Science:
- Gastroenterology
- Pulmonology
- Surgical Innovation
Background:
- Gastroesophageal reflux (GER) is often comorbid with asthma.
- The impact of antireflux surgery on adult asthma symptoms is not fully understood.
Purpose of the Study:
- To evaluate the efficacy of antireflux surgery in adults experiencing both GER and asthma.
Main Methods:
- 13 adult patients with GER and asthma underwent antireflux surgery.
- Diagnosis of GER confirmed via esophagoscopy, manometry, and esophageal pH testing.
- Postoperative follow-up ranged from 13 months to 5 years.
Main Results:
- 6 patients experienced complete resolution of wheezing.
- 6 patients had markedly decreased wheezing frequency and severity.
- 4 of 11 patients on chronic bronchodilators stopped therapy; 6 reduced dosage.
- 2 of 7 corticosteroid-dependent patients were weaned off medication.
Conclusions:
- Surgical correction of GER can significantly alleviate pulmonary symptoms in select adults.
- Antireflux surgery may reduce the need for asthma medications.
- Further research is warranted to explore the GER-asthma connection and surgical outcomes.