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Symptomatic SARS-CoV2 infection associated with high mortality in AA amyloidosis

Rim Bourguiba1,2, Alexandre Terré1,2, Lea Savey1,2

  • 1Internal Medicine Department, Tenon Hospital, AP-HP, Paris, France.

Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis
|December 21, 2023
PubMed
Abstract

No abstract available in PubMed .

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Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
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