Current trends in macromolecular model refinement and validation

Area of Science:

• Crystallography and structural biology
• Computational chemistry and bioinformatics

Background:

• The Collaborative Computational Project, Number 4 (CCP4) is a cornerstone in the field of protein crystallography.
• The annual CCP4 Study Weekend serves as a vital forum for presenting and discussing new developments.

Purpose of the Study:

• To introduce a special issue compiling research presented at the CCP4 Study Weekend 2022.
• To provide a gateway to cutting-edge articles in crystallographic software and methodology.

Main Methods:

• This section is not applicable as the abstract is an introduction to a collection of articles.
• The articles themselves cover various computational methods in structural biology.

Main Results:

• The special issue features a diverse range of topics discussed at the 2022 CCP4 Study Weekend.
• Key advancements in crystallographic data processing and analysis are highlighted.

Conclusions:

• The collection of articles represents the forefront of research in crystallographic computing.
• This special issue is a valuable resource for researchers in structural biology and related fields.