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Embedding Mixed Sorbents in Binder: Solid-Phase Microextraction Coating with Wide Extraction Coverage and Its
Wei Zhou1, Kai Hu1,2, Yuanpeng Wang1
1Department of Chemistry, University of Waterloo, Waterloo, ON N2L 3G1, Canada.
Environmental Science & Technology
|December 21, 2023
Summary
A novel mixed-coating solid-phase microextraction (SPME) device effectively analyzes diverse water contaminants. This versatile tool enhances environmental water quality assessment for various pollutants.
Area of Science:
- Environmental Chemistry
- Analytical Chemistry
- Materials Science
Background:
- Solid-phase microextraction (SPME) is crucial for water analysis but faces limitations in extraction coverage for multiple contaminants.
- Existing SPME devices often struggle to efficiently extract a wide range of polar, nonpolar, and charged compounds simultaneously.
Purpose of the Study:
- To develop a novel SPME coating strategy using a mixture of sorbent particles for comprehensive water analysis.
- To create a single SPME device capable of extracting diverse environmental contaminants, including polar, nonpolar, and charged species.
Main Methods:
- Preparation of SPME blades by mixing hydrophobic/lipophilic balanced (HLB), HLB-weak cationic exchange (HLB-WCX), and HLB-weak anionic exchange (HLB-WAX) sorbent particles with a polyacrylonitrile (PAN) binder.
- Development of three analytical methodologies: high-throughput SPME-LC-MS/MS, in-bottle SPME-LC-high resolution MS (HRMS), and on-site drone sampling SPME-LC-HRMS.
- Characterization of the mixed-coating's matrix compatibility and porous filter properties.
Main Results:
- The mixed-coating SPME device demonstrated effective extraction for polar and nonpolar, as well as positively and negatively charged compounds.
- Successful application in quantitative analysis of drugs of abuse and artificial sweeteners, and untargeted screening of organic contaminants in water.
- The PAN binder provided matrix compatibility and acted as a porous filter, preventing contamination from large molecules.
Conclusions:
- The developed mixed-coating SPME device offers a versatile and efficient solution for comprehensive environmental water analysis.
- This strategy enables robust water quality assessment using a single, multi-functional SPME device.
- The integration with LC-MS/MS and HRMS platforms facilitates both targeted and untargeted contaminant screening.
Keywords:
LC−MSextraction coveragemix-sorbents coatingsolid-phase microextractionuntargeted screeningwater analysisMore Related Videos
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